This web portal was developed as part of the
Leucegene
project.
Overview
The Surface Protein Annotation Tool (SPAT) is a
user-friendly tool that scores proteins according to
the chance they have to be located at the cell
surface.
In brief
SPAT calculates a basic score for each protein based on the
combinations of selected (and regularly updated)
annotations/terms extracted from multiple public proteomic
databases, which is then weighted according to the eventual
accumulation of “black-listed” annotation flags.
SPAT output also contains a series of public
(when available) and in-house annotations including the
verified main locations and references to verified antibodies
targeting annotated proteins, the pubmed references for
protein/term associations, as well as expression data and
protein levels in essential human organs and normal
haematopoietic progenitors (Leucegene Hemogene expression data),
making it a helpful tool for the identification of immunotherapy
targets.
See publication for more details
If you used SPAT for your research project, please cite: